BAIT
VAMP4
D1Ertd147e
vesicle-associated membrane protein 4
GO Process (8)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
STX3
Syn-3
syntaxin 3
GO Process (12)
GO Function (4)
GO Component (16)
Gene Ontology Biological Process
- exocytosis [IMP]
- intracellular protein transport [IBA]
- long-term synaptic potentiation [IMP]
- membrane fusion [ISO]
- neuron projection development [ISO]
- positive regulation of cell adhesion [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of chemotaxis [ISO]
- positive regulation of protein localization to cell surface [ISO]
- positive regulation of protein localization to plasma membrane [ISO]
- synaptic vesicle fusion to presynaptic membrane [IBA]
- vesicle docking [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- SNARE complex [IBA, ISO]
- apical plasma membrane [IDA, ISO]
- azurophil granule [ISO]
- cell [IMP]
- cell-cell junction [ISO]
- dendrite [IDA]
- extracellular vesicular exosome [ISO]
- growth cone [ISO]
- integral component of membrane [IBA]
- lamellipodium [ISO]
- membrane [IDA]
- neuron projection [ISO]
- plasma membrane [ISO]
- secretory granule [IDA]
- specific granule [ISO]
- synaptic vesicle [IBA]
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.955 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID