BAIT
FBXW11
2310065A07Rik, AA536858, BTRC2, BTRCP2, Fbxw1b, HOS, RP23-94F11.1
F-box and WD-40 domain protein 11
GO Process (11)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [IMP, ISO]
- negative regulation of NF-kappaB import into nucleus [IMP]
- negative regulation of transcription, DNA-templated [ISO]
- positive regulation of circadian rhythm [IMP]
- positive regulation of proteolysis [ISO]
- positive regulation of transcription, DNA-templated [IMP]
- proteasome-mediated ubiquitin-dependent protein catabolic process [ISO]
- protein dephosphorylation [IDA]
- protein destabilization [ISO]
- protein polyubiquitination [IDA, ISO]
- protein ubiquitination [ISO]
Gene Ontology Molecular Function
Mus musculus
PREY
TACC1
4833447E04Rik, AA960202, B230378H13Rik
transforming, acidic coiled-coil containing protein 1
GO Process (6)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.796 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID