BAIT
ILK
AA511515, ESTM24
integrin linked kinase
GO Process (43)
GO Function (7)
GO Component (16)
Gene Ontology Biological Process
- Schwann cell development [IMP]
- branching involved in ureteric bud morphogenesis [IDA]
- cell aging [ISO]
- cell cycle arrest [ISO]
- cell projection organization [IMP]
- establishment or maintenance of epithelial cell apical/basal polarity [IMP]
- extracellular fibril organization [ISO]
- fibroblast migration [IMP]
- integrin-mediated signaling pathway [ISO]
- myelin assembly [ISO]
- myelination in peripheral nervous system [IMP]
- negative regulation of apoptotic process [ISO]
- negative regulation of cardiac muscle cell apoptotic process [ISO]
- negative regulation of neural precursor cell proliferation [IGI, IMP]
- negative regulation of neuron apoptotic process [ISO]
- negative regulation of protein kinase activity [ISO]
- negative regulation of smooth muscle cell migration [ISO]
- negative regulation of smooth muscle cell proliferation [ISO]
- nerve development [IMP]
- neuron projection morphogenesis [ISO]
- peptidyl-serine phosphorylation [IMP, ISO]
- platelet aggregation [ISO]
- positive regulation of BMP signaling pathway [IMP]
- positive regulation of MAP kinase activity [ISO]
- positive regulation of MAPK cascade [ISO]
- positive regulation of axon extension [ISO]
- positive regulation of axonogenesis [ISO]
- positive regulation of canonical Wnt signaling pathway [ISO]
- positive regulation of cell migration [ISO]
- positive regulation of cell proliferation [IMP, ISO]
- positive regulation of cell-matrix adhesion [ISO]
- positive regulation of dendrite morphogenesis [ISO]
- positive regulation of myoblast differentiation [ISO]
- positive regulation of osteoblast differentiation [IMP]
- positive regulation of phosphorylation [ISO]
- positive regulation of protein kinase B signaling [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- protein heterooligomerization [ISO]
- protein kinase B signaling [IMP]
- protein phosphorylation [ISO]
- regulation of actin cytoskeleton organization [ISO]
- regulation of cell growth [ISO]
- substrate adhesion-dependent cell spreading [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- axon [ISO]
- cell junction [ISO]
- cell-cell junction [ISO]
- costamere [ISO]
- cytoplasm [ISO]
- dendritic shaft [ISO]
- extracellular matrix [ISO]
- focal adhesion [IDA, ISA, ISO]
- intracellular [IMP]
- lamellipodium [IDA]
- membrane [ISO]
- neuronal cell body [ISO]
- nucleoplasm [ISO]
- protein complex [ISO]
- stress fiber [ISO]
- terminal bouton [ISO]
Mus musculus
PREY
TECR
2410016D23Rik, A230102P12Rik, AI173355, D17Ertd178e, Gpsn2, SC2
trans-2,3-enoyl-CoA reductase
GO Process (2)
GO Function (0)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.929 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID