BAIT
MYCN
N-myc, Nmyc, Nmyc-1, Nmyc1, bHLHe37, c-nmyc
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
GO Process (12)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
- branching morphogenesis of an epithelial tube [IMP]
- cartilage condensation [IMP]
- embryonic digit morphogenesis [IMP]
- embryonic skeletal system morphogenesis [IMP]
- lung development [IMP]
- negative regulation of astrocyte differentiation [IDA]
- negative regulation of reactive oxygen species metabolic process [IDA]
- positive regulation of cell death [IMP]
- positive regulation of cell proliferation [IMP]
- positive regulation of mesenchymal cell proliferation [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of transcription, DNA-templated [IDA]
Gene Ontology Molecular Function
Mus musculus
PREY
TRIM32
1810045E12Rik, 3f3, BBS11, Zfp117, RP23-468K2.1
tripartite motif-containing 32
GO Process (22)
GO Function (8)
GO Component (3)
Gene Ontology Biological Process
- actin ubiquitination [IDA]
- innate immune response [ISO]
- negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [ISO]
- negative regulation of keratinocyte apoptotic process [NAS]
- negative regulation of viral release from host cell [ISO]
- negative regulation of viral transcription [ISO]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [ISO]
- positive regulation of NF-kappaB transcription factor activity [IDA, ISO]
- positive regulation of cell cycle [ISO]
- positive regulation of cell growth [ISO]
- positive regulation of cell migration [ISO]
- positive regulation of cell motility [IDA]
- positive regulation of neurogenesis [IDA]
- positive regulation of neuron differentiation [IDA]
- positive regulation of protein catabolic process [IDA]
- positive regulation of proteolysis [ISO]
- positive regulation of sequence-specific DNA binding transcription factor activity [ISO]
- protein polyubiquitination [ISO]
- protein ubiquitination [IDA, ISO]
- protein ubiquitination involved in ubiquitin-dependent protein catabolic process [ISO]
- response to UV [IDA]
- response to tumor necrosis factor [IDA]
Gene Ontology Molecular Function
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.966 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID