BAIT
UBR4
1810009A16Rik, A930005E13Rik, D930005K06Rik, Gm1032, Gm1666, N28143, RBAF600, Zubr1, mKIAA0462, p600
ubiquitin protein ligase E3 component n-recognin 4
GO Process (1)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
UBE2A
HHR6A, HR6A, Mhr6a, RP23-286I5.4
ubiquitin-conjugating enzyme E2A
GO Process (13)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- DNA repair [IBA, ISO]
- histone H2A ubiquitination [ISO]
- histone ubiquitination [IBA]
- in utero embryonic development [IGI, IMP]
- maternal process involved in female pregnancy [IMP]
- positive regulation of cell proliferation [ISO]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IBA]
- protein K11-linked ubiquitination [ISO]
- protein K48-linked ubiquitination [ISO]
- protein autoubiquitination [ISO]
- protein polyubiquitination [IBA]
- protein ubiquitination [IGI]
- response to UV [ISO]
Gene Ontology Molecular Function
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.703 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID