BAIT
BDH1
2310032J20Rik, AI327223, Bdh
3-hydroxybutyrate dehydrogenase, type 1
GO Process (1)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
USP47
4930502N04Rik, A630020C16Rik
ubiquitin specific peptidase 47
GO Process (15)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- base-excision repair [IBA, ISO]
- cellular response to DNA damage stimulus [ISO]
- cellular response to UV [IMP]
- monoubiquitinated protein deubiquitination [ISO]
- negative regulation of G2/M transition of mitotic cell cycle [ISO, ISS]
- negative regulation of apoptotic process [ISO]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO, ISS]
- negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [IMP]
- negative regulation of transcription, DNA-templated [IBA, ISO, ISS]
- positive regulation of cell growth [ISO, ISS]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IBA]
- protein deubiquitination [IBA]
- proteolysis [ISO]
- regulation of proteasomal protein catabolic process [IBA]
- response to drug [ISO, ISS]
Gene Ontology Molecular Function
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.809 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID