BAIT
PCID2
A730042J05Rik
PCI domain containing 2
GO Process (7)
GO Function (0)
GO Component (0)
Gene Ontology Biological Process
- negative regulation of apoptotic process [IMP, ISO]
- negative regulation of cysteine-type endopeptidase activity [ISO]
- positive regulation of B cell differentiation [IMP]
- positive regulation of mitotic cell cycle spindle assembly checkpoint [IMP, ISO]
- positive regulation of transcription, DNA-templated [IMP, ISO]
- regulation of mRNA stability [ISO]
- spleen development [IMP]
Mus musculus
PREY
VPS52
ARE1, D130068D18, D430041K17Rik, SAC2, Sacm2l, tclw5
vacuolar protein sorting 52 (yeast)
GO Process (2)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.829 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID