BAIT
DNMT1
Cxxc9, Dnmt, Dnmt1o, MCMT, MTase, Met-1, Met1, MommeD2, m.MmuI
DNA methyltransferase (cytosine-5) 1
GO Process (20)
GO Function (15)
GO Component (7)
Gene Ontology Biological Process
- C-5 methylation of cytosine [IDA]
- DNA hypermethylation [ISO]
- DNA methylation [IDA, IMP]
- DNA methylation on cytosine [ISO]
- DNA methylation on cytosine within a CG sequence [ISO]
- S-adenosylhomocysteine metabolic process [ISO]
- S-adenosylmethioninamine metabolic process [ISO]
- S-adenosylmethionine metabolic process [ISO]
- cellular response to amino acid stimulus [IDA]
- cellular response to transforming growth factor beta stimulus [ISO]
- gene silencing [IDA]
- maintenance of DNA methylation [IMP, ISO]
- negative regulation of histone H3-K9 methylation [ISO]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- positive regulation of gene expression [ISO]
- positive regulation of histone H3-K4 methylation [ISO]
- regulation of cell proliferation [IGI]
- regulation of gene expression [IMP]
- response to antidepressant [ISO]
Gene Ontology Molecular Function- DNA (cytosine-5-)-methyltransferase activity [IDA, ISO]
- DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates [ISO]
- DNA binding [IDA, ISO]
- DNA-methyltransferase activity [ISO]
- RNA binding [IDA]
- chromatin binding [IDA]
- double-stranded DNA binding [ISO]
- estrogen receptor binding [ISO]
- histone deacetylase binding [ISO]
- methyl-CpG binding [IDA, ISO]
- methyltransferase activity [IDA]
- protein binding [IPI]
- protein domain specific binding [ISO]
- unmethylated CpG binding [ISO]
- zinc ion binding [IDA]
- DNA (cytosine-5-)-methyltransferase activity [IDA, ISO]
- DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates [ISO]
- DNA binding [IDA, ISO]
- DNA-methyltransferase activity [ISO]
- RNA binding [IDA]
- chromatin binding [IDA]
- double-stranded DNA binding [ISO]
- estrogen receptor binding [ISO]
- histone deacetylase binding [ISO]
- methyl-CpG binding [IDA, ISO]
- methyltransferase activity [IDA]
- protein binding [IPI]
- protein domain specific binding [ISO]
- unmethylated CpG binding [ISO]
- zinc ion binding [IDA]
Gene Ontology Cellular Component
Mus musculus
PREY
ZFP57
G19, Zfp-57
zinc finger protein 57
GO Process (3)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.888 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID