BAIT
TEX101
CT131, GTPR867, NYD-SP8, PRO1884, SGRG, SPATA44, TES101RP, UNQ867/PRO1884
testis expressed 101
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
THY1
CD90
Thy-1 cell surface antigen
GO Process (13)
GO Function (4)
GO Component (9)
Gene Ontology Biological Process
- T cell receptor signaling pathway [ISS]
- angiogenesis [ISS]
- cytoskeleton organization [ISS]
- focal adhesion assembly [ISS]
- negative regulation of T cell receptor signaling pathway [ISS]
- negative regulation of axonogenesis [ISS]
- negative regulation of cell migration [ISS]
- negative regulation of protein kinase activity [ISS]
- positive regulation of GTPase activity [ISS]
- positive regulation of T cell activation [ISS]
- positive regulation of release of sequestered calcium ion into cytosol [ISS]
- retinal cone cell development [ISS]
- single organismal cell-cell adhesion [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies.
TEX101 is a testis-specific protein expressed exclusively in male germ cells and is a validated biomarker of male infertility. Studies in mice suggest that TEX101 is a cell-surface chaperone which regulates, through protein-protein interactions, the maturation of proteins involved in spermatozoa transit and oocyte binding. Male TEX101-null mice are sterile. Here, we identified by co-immunoprecipitation-mass spectrometry the interactome of human ... [more]
Mol. Cell Proteomics Dec. 01, 2017; 17(12);2480-2495 [Pubmed: 30097533]
Throughput
- High Throughput
Curated By
- BioGRID