BAIT

TEX101

CT131, GTPR867, NYD-SP8, PRO1884, SGRG, SPATA44, TES101RP, UNQ867/PRO1884

testis expressed 101

GO Process (0)

GO Function (0)

GO Component (0)

CRISPR Database OMIM VEGA HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

PREY

CYB5B

CYB5-M, CYPB5M, OMB5, RP11-140H17.1

cytochrome b5 type B (outer mitochondrial membrane)

GO Process (0)

GO Function (1)

GO Component (1)

Gene Ontology Molecular Function

heme binding [IDA]

Gene Ontology Cellular Component

membrane [IDA]

CRISPR Database OMIM HGNC Alliance of Genome Resources VEGA Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies.

Schiza C, Korbakis D, Panteleli E, Jarvi K, Drabovich AP, Diamandis EP

TEX101 is a testis-specific protein expressed exclusively in male germ cells and is a validated biomarker of male infertility. Studies in mice suggest that TEX101 is a cell-surface chaperone which regulates, through protein-protein interactions, the maturation of proteins involved in spermatozoa transit and oocyte binding. Male TEX101-null mice are sterile. Here, we identified by co-immunoprecipitation-mass spectrometry the interactome of human ... [more]

Mol. Cell Proteomics Dec. 01, 2017; 17(12);2480-2495 [Pubmed: 30097533]

Throughput

High Throughput

Curated By

BioGRID

Interaction Summary