GRID2
Gene Ontology Biological Process
- cellular protein localization [ISS]
- cerebellar granule cell differentiation [ISS]
- glutamate receptor signaling pathway [TAS]
- heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [ISS]
- ion transmembrane transport [IBA]
- ionotropic glutamate receptor signaling pathway [IBA]
- prepulse inhibition [ISS]
- regulation of excitatory postsynaptic membrane potential [ISS]
- regulation of neuron apoptotic process [ISS]
- synaptic transmission, glutamatergic [IBA, ISS]
- transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
GRIK2
Gene Ontology Biological Process
- glutamate receptor signaling pathway [TAS]
- ion transmembrane transport [IBA]
- ionotropic glutamate receptor signaling pathway [IBA]
- positive regulation of synaptic transmission [IMP]
- regulation of short-term neuronal synaptic plasticity [IMP]
- regulation of synaptic transmission [IDA]
- synaptic transmission [TAS]
- synaptic transmission, glutamatergic [IBA]
- transport [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Heteromer formation of delta2 glutamate receptors with AMPA or kainate receptors.
The delta2 glutamate receptor (GluRdelta2) is predominantly expressed in the postsynaptic densities of parallel fiber-Purkinje cell synapses and plays a crucial role in cerebellar function. However, the mechanisms by which GluRdelta2 participates in cerebellar functions are largely unknown because GluRdelta2 does not bind glutamate analogs. We investigated the possibility that GluRdelta2 may be involved in channel formation together with other ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| GRIK2 GRID2 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID