BAIT

TWD1

ATFKBP42, FK506-BINDING PROTEIN 42, FKBP42, TWISTED DWARF 1, UCU2, ULTRACURVATA 2, AT3G21640
putative peptidyl-prolyl cis-trans isomerase FKBP42
GO Process (2)
GO Function (4)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Arabidopsis thaliana (Columbia)
PREY

MRP2

ABC TRANSPORTER, ATMRP2, EST4, T29F13.13, T29F13_13, multidrug resistance-associated protein 2, AT2G34660
ABC transporter C family member 2
Arabidopsis thaliana (Columbia)

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Arabidopsis immunophilin-like TWD1 functionally interacts with vacuolar ABC transporters.

Geisler M, Girin M, Brandt S, Vincenzetti V, Plaza S, Paris N, Kobae Y, Maeshima M, Billion K, Kolukisaoglu UH, Schulz B, Martinoia E

Previously, the immunophilin-like protein TWD1 from Arabidopsis has been demonstrated to interact with the ABC transporters AtPGP1 and its closest homologue, AtPGP19. Physiological and biochemical investigation of pgp1/pgp19 and of twd1 plants suggested a regulatory role of TWD1 on AtPGP1/AtPGP19 transport activities. To further understand the dramatic pleiotropic phenotype that is caused by loss-of-function mutation of the TWD1 gene, we ... [more]

Mol. Biol. Cell Jul. 01, 2004; 15(7);3393-405 [Pubmed: 15133126]

Throughput

  • Low Throughput

Curated By

  • BioGRID