BAIT

FAM168B

family with sequence similarity 168, member B
GO Process (0)
GO Function (0)
GO Component (1)

Gene Ontology Cellular Component

Rattus norvegicus

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

The novel protein MANI modulates neurogenesis and neurite-cone growth.

Mishra M, Akatsu H, Heese K

Neuronal regeneration and axonal re-growth in the injured mammalian central nervous system remains an unsolved field. To date, three myelin-associated proteins [Nogo or reticulon 4 (RTN4), myelin-associated glycoprotein (MAG) and oligodendrocyte myelin glycoprotein (OMG)] are known to inhibit axonal regeneration via activation of the neuronal glycosylphosphatidylinositol-anchored Nogo receptor [NgR, together with p75 neurotrophin receptor (p75NTR) and Lingo-1]. In the present ... [more]

J. Cell. Mol. Med. Aug. 01, 2011; 15(8);1713-25 [Pubmed: 20716133]

Throughput

  • Low Throughput

Curated By

  • BioGRID