BAIT
GRIN2D
GluN2D, NMDAR2D, NR2D
glutamate receptor, ionotropic, NMDA2D (epsilon 4)
GO Process (11)
GO Function (7)
GO Component (4)
Gene Ontology Biological Process
- adult locomotory behavior [IMP]
- cation transmembrane transport [ISO]
- cation transport [ISO]
- detection of mechanical stimulus involved in sensory perception of pain [IMP]
- ion transmembrane transport [IMP]
- ionotropic glutamate receptor signaling pathway [IMP, ISO]
- regulation of excitatory postsynaptic membrane potential [IMP]
- regulation of ion transmembrane transport [ISO]
- regulation of sensory perception of pain [IMP]
- startle response [IMP]
- synaptic transmission, glutamatergic [IBA, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CTBP1
BARS, CtBP1-L, CtBP1-S, CtBP3/BARS, D4S115h, D5H4S115, D5H4S115E
C-terminal binding protein 1
GO Process (10)
GO Function (8)
GO Component (5)
Gene Ontology Biological Process
- Golgi organization [ISO]
- chromatin organization involved in regulation of transcription [ISO]
- negative regulation of histone H4 acetylation [ISO]
- negative regulation of histone acetylation [ISO]
- negative regulation of transcription from RNA polymerase II promoter [IMP, ISO]
- negative regulation of transcription, DNA-templated [IDA]
- positive regulation of histone deacetylation [ISO]
- regulation of cell cycle [ISO]
- transcription from RNA polymerase II promoter [ISO]
- white fat cell differentiation [IDA]
Gene Ontology Molecular Function- NAD binding [ISO]
- RNA polymerase II transcription corepressor activity [ISO]
- protein binding [IPI]
- protein domain specific binding [ISO]
- protein homodimerization activity [ISO]
- repressing transcription factor binding [ISO]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription factor binding [IPI, ISO]
- NAD binding [ISO]
- RNA polymerase II transcription corepressor activity [ISO]
- protein binding [IPI]
- protein domain specific binding [ISO]
- protein homodimerization activity [ISO]
- repressing transcription factor binding [ISO]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription factor binding [IPI, ISO]
Gene Ontology Cellular Component
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Identification of C-Terminal Binding Protein 1 as a Novel NMDA Receptor Interactor.
A new N-methyl D aspartate neurotransmitter receptor interacting protein has been identified by yeast two-hybrid screening of a mouse brain cDNA library. C-terminal binding protein 1 (CtBP1) was shown to associate with the intracellular C-terminal regions of the N-methyl D aspartate receptor subunits GluN2A and GluN2D but not with GluN1-1a cytoplasmic C-terminal region. In yeast mating assays using a series ... [more]
Neurochem. Res. Jun. 01, 2019; 44(6);1437-1445 [Pubmed: 30284099]
Throughput
- Low Throughput
Curated By
- BioGRID