BAIT
GRIA4
GluA4, GluR-D, GluR4
glutamate receptor, ionotropic, AMPA 4
GO Process (7)
GO Function (4)
GO Component (10)
Gene Ontology Biological Process
- ion transmembrane transport [IBA]
- ionotropic glutamate receptor signaling pathway [IDA, IMP, ISO, TAS]
- positive regulation of synaptic transmission, glutamatergic [IMP]
- regulation of synapse structure or activity [TAS]
- regulation of synaptic transmission [IMP]
- response to fungicide [IEP]
- synaptic transmission [IMP, TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [IDA, ISO]
- dendrite [IDA, IMP]
- ionotropic glutamate receptor complex [TAS]
- kainate selective glutamate receptor complex [IDA]
- neuronal cell body [IDA]
- postsynaptic density [IDA]
- postsynaptic membrane [IBA]
- synapse [IMP, ISO]
- terminal bouton [IDA]
- vesicle [ISO]
Rattus norvegicus
PREY
MYO5A
D, Dop, Myh12
myosin VA
GO Process (29)
GO Function (14)
GO Component (29)
Gene Ontology Biological Process
- actin filament-based movement [IDA, ISO]
- cellular response to insulin stimulus [ISO, ISS]
- developmental pigmentation [ISO]
- endoplasmic reticulum localization [ISO]
- exocytosis [ISO]
- insulin secretion [ISO]
- locomotion involved in locomotory behavior [ISO]
- long-chain fatty acid biosynthetic process [ISO]
- melanin biosynthetic process [ISO]
- melanin metabolic process [ISO]
- melanocyte differentiation [ISO]
- melanosome localization [ISO]
- melanosome transport [ISO]
- metabolic process [IDA, IMP]
- myelination [ISO]
- neuromuscular process controlling balance [ISO]
- odontogenesis [ISO]
- pigmentation [IMP, ISO]
- post-Golgi vesicle-mediated transport [ISO]
- protein localization to plasma membrane [ISO, ISS]
- regulation of Golgi organization [ISO]
- regulation of exocytosis [IMP]
- regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [ISO]
- secretory granule localization [IDA, IMP, ISO]
- synapse organization [ISO]
- synaptic transmission [ISO]
- vesicle transport along actin filament [IMP, ISO]
- vesicle-mediated transport [ISO, ISS]
- visual perception [ISO]
Gene Ontology Molecular Function- ATP binding [IDA]
- ATP-dependent protein binding [IPI]
- Rab GTPase binding [ISO]
- SNARE binding [IPI]
- actin binding [ISO]
- calcium ion binding [ISO]
- calcium-dependent protein binding [IPI]
- calmodulin binding [ISO]
- microfilament motor activity [IDA, ISO]
- motor activity [IMP, ISO]
- poly(A) RNA binding [ISO]
- protein dimerization activity [IMP]
- protein heterodimerization activity [IDA]
- syntaxin-1 binding [IPI]
- ATP binding [IDA]
- ATP-dependent protein binding [IPI]
- Rab GTPase binding [ISO]
- SNARE binding [IPI]
- actin binding [ISO]
- calcium ion binding [ISO]
- calcium-dependent protein binding [IPI]
- calmodulin binding [ISO]
- microfilament motor activity [IDA, ISO]
- motor activity [IMP, ISO]
- poly(A) RNA binding [ISO]
- protein dimerization activity [IMP]
- protein heterodimerization activity [IDA]
- syntaxin-1 binding [IPI]
Gene Ontology Cellular Component
- Golgi apparatus [ISO]
- actin filament [ISO]
- actomyosin [ISO]
- actomyosin, myosin complex part [IDA]
- axon [IDA]
- cell [ISO]
- cytoplasm [IDA, ISO]
- cytosol [ISO]
- early endosome [ISO]
- endoplasmic reticulum [ISO]
- extracellular vesicular exosome [ISO]
- filopodium tip [ISO]
- insulin-responsive compartment [ISO, ISS]
- intermediate filament [ISO]
- late endosome [ISO]
- lysosome [ISO]
- melanosome [ISO]
- membrane [ISO]
- microtubule plus-end [ISO]
- myosin complex [ISO]
- neuron projection [IDA]
- neuronal cell body [IDA, ISO]
- peroxisome [ISO]
- photoreceptor outer segment [ISO]
- recycling endosome [ISO]
- ruffle [ISO]
- secretory granule [IDA, ISO, TAS]
- synaptic vesicle [IDA]
- vesicle [ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic analysis of an interactome for long-form AMPA receptor subunits.
Glutamate receptors of the AMPA-type mediate fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity. The binding of these receptors to a variety of proteins is known to regulate their targeting to the synapse and consequently to modulate synaptic strength, as well as to modify receptor characteristics. In this study, a proteomic screening ... [more]
J. Proteome Res. Apr. 05, 2010; 9(4);1670-82 [Pubmed: 20131911]
Throughput
- High Throughput
Curated By
- BioGRID