BAIT
GRIA4
GluA4, GluR-D, GluR4
glutamate receptor, ionotropic, AMPA 4
GO Process (7)
GO Function (4)
GO Component (10)
Gene Ontology Biological Process
- ion transmembrane transport [IBA]
- ionotropic glutamate receptor signaling pathway [IDA, IMP, ISO, TAS]
- positive regulation of synaptic transmission, glutamatergic [IMP]
- regulation of synapse structure or activity [TAS]
- regulation of synaptic transmission [IMP]
- response to fungicide [IEP]
- synaptic transmission [IMP, TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [IDA, ISO]
- dendrite [IDA, IMP]
- ionotropic glutamate receptor complex [TAS]
- kainate selective glutamate receptor complex [IDA]
- neuronal cell body [IDA]
- postsynaptic density [IDA]
- postsynaptic membrane [IBA]
- synapse [IMP, ISO]
- terminal bouton [IDA]
- vesicle [ISO]
Rattus norvegicus
PREY
VIM
vimentin
GO Process (21)
GO Function (12)
GO Component (16)
Gene Ontology Biological Process
- Bergmann glial cell differentiation [ISO]
- SMAD protein signal transduction [ISO]
- aging [IEP]
- astrocyte development [ISO]
- cellular response to fibroblast growth factor stimulus [IEP]
- decidualization [IEP]
- fat cell differentiation [IEP]
- intermediate filament organization [ISO]
- intermediate filament-based process [ISO]
- lens fiber cell development [ISO]
- negative regulation of neuron projection development [ISO]
- positive regulation of gene expression [ISO]
- positive regulation of glial cell proliferation [IMP]
- regulation of Schwann cell migration [IDA]
- regulation of axonogenesis [IDA]
- response to estradiol [IEP]
- response to radiation [IEP]
- response to selenium ion [IEP]
- response to vitamin D [IEP]
- response to zinc ion [IEP]
- skeletal muscle tissue regeneration [IEP]
Gene Ontology Molecular Function- double-stranded RNA binding [ISO]
- glycoprotein binding [ISO]
- identical protein binding [ISO]
- kinase binding [IPI]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein kinase binding [IPI]
- protein phosphatase 2A binding [IDA]
- scaffold protein binding [ISO]
- structural constituent of cytoskeleton [ISO, ISS]
- structural constituent of eye lens [ISO]
- structural molecule activity [ISO, TAS]
- double-stranded RNA binding [ISO]
- glycoprotein binding [ISO]
- identical protein binding [ISO]
- kinase binding [IPI]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein kinase binding [IPI]
- protein phosphatase 2A binding [IDA]
- scaffold protein binding [ISO]
- structural constituent of cytoskeleton [ISO, ISS]
- structural constituent of eye lens [ISO]
- structural molecule activity [ISO, TAS]
Gene Ontology Cellular Component
- axon [IDA]
- cell body [IDA]
- cell leading edge [ISO]
- cell projection [IDA, ISO]
- cytoplasm [IDA, ISO, ISS]
- cytoskeleton [IDA, ISO]
- cytosol [IDA, ISO]
- extracellular vesicular exosome [ISO]
- focal adhesion [ISO]
- intermediate filament [ISO, ISS]
- intermediate filament cytoskeleton [ISO]
- neuron projection [ISO]
- perinuclear region of cytoplasm [IDA]
- peroxisome [ISO]
- plasma membrane [ISO]
- type III intermediate filament [TAS]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic analysis of an interactome for long-form AMPA receptor subunits.
Glutamate receptors of the AMPA-type mediate fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity. The binding of these receptors to a variety of proteins is known to regulate their targeting to the synapse and consequently to modulate synaptic strength, as well as to modify receptor characteristics. In this study, a proteomic screening ... [more]
J. Proteome Res. Apr. 05, 2010; 9(4);1670-82 [Pubmed: 20131911]
Throughput
- High Throughput
Curated By
- BioGRID