BAIT
GRIA4
GluA4, GluR-D, GluR4
glutamate receptor, ionotropic, AMPA 4
GO Process (7)
GO Function (4)
GO Component (10)
Gene Ontology Biological Process
- ion transmembrane transport [IBA]
- ionotropic glutamate receptor signaling pathway [IDA, IMP, ISO, TAS]
- positive regulation of synaptic transmission, glutamatergic [IMP]
- regulation of synapse structure or activity [TAS]
- regulation of synaptic transmission [IMP]
- response to fungicide [IEP]
- synaptic transmission [IMP, TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [IDA, ISO]
- dendrite [IDA, IMP]
- ionotropic glutamate receptor complex [TAS]
- kainate selective glutamate receptor complex [IDA]
- neuronal cell body [IDA]
- postsynaptic density [IDA]
- postsynaptic membrane [IBA]
- synapse [IMP, ISO]
- terminal bouton [IDA]
- vesicle [ISO]
Rattus norvegicus
PREY
MYH9
myosin, heavy chain 9, non-muscle
GO Process (14)
GO Function (9)
GO Component (15)
Gene Ontology Biological Process
- ATP catabolic process [ISS]
- actin cytoskeleton reorganization [ISS]
- actin filament-based movement [ISS]
- angiogenesis [ISS]
- blood vessel endothelial cell migration [ISS]
- membrane protein ectodomain proteolysis [ISS]
- monocyte differentiation [ISS]
- platelet formation [ISS]
- positive regulation of calcium ion transport into cytosol [IMP]
- positive regulation of endocytosis [IMP]
- positive regulation of phagocytosis [IMP]
- protein transport [ISS]
- regulation of cell shape [ISS]
- sodium ion transmembrane transport [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- actin cytoskeleton [ISS]
- actomyosin contractile ring [ISS]
- cell leading edge [ISS]
- cleavage furrow [ISS]
- cytoplasm [IDA, ISS]
- cytosol [ISS]
- endosome [IDA]
- integrin complex [ISS]
- lateral plasma membrane [IDA]
- nucleus [ISS]
- phagocytic vesicle [IDA]
- plasma membrane [ISS]
- protein complex [IDA, ISS]
- ruffle [ISS]
- stress fiber [ISS]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic analysis of an interactome for long-form AMPA receptor subunits.
Glutamate receptors of the AMPA-type mediate fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity. The binding of these receptors to a variety of proteins is known to regulate their targeting to the synapse and consequently to modulate synaptic strength, as well as to modify receptor characteristics. In this study, a proteomic screening ... [more]
J. Proteome Res. Apr. 05, 2010; 9(4);1670-82 [Pubmed: 20131911]
Throughput
- High Throughput
Curated By
- BioGRID