BAIT
GRIA4
GluA4, GluR-D, GluR4
glutamate receptor, ionotropic, AMPA 4
GO Process (7)
GO Function (4)
GO Component (10)
Gene Ontology Biological Process
- ion transmembrane transport [IBA]
- ionotropic glutamate receptor signaling pathway [IDA, IMP, ISO, TAS]
- positive regulation of synaptic transmission, glutamatergic [IMP]
- regulation of synapse structure or activity [TAS]
- regulation of synaptic transmission [IMP]
- response to fungicide [IEP]
- synaptic transmission [IMP, TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [IDA, ISO]
- dendrite [IDA, IMP]
- ionotropic glutamate receptor complex [TAS]
- kainate selective glutamate receptor complex [IDA]
- neuronal cell body [IDA]
- postsynaptic density [IDA]
- postsynaptic membrane [IBA]
- synapse [IMP, ISO]
- terminal bouton [IDA]
- vesicle [ISO]
Rattus norvegicus
PREY
NCAM1
Cd56, N-CAM, N-CAM-1, NCAM-1, NCAM-C, NCAMC, Ncam
neural cell adhesion molecule 1
GO Process (23)
GO Function (6)
GO Component (11)
Gene Ontology Biological Process
- aging [IDA]
- calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [TAS]
- cell adhesion [TAS]
- cell surface receptor signaling pathway [ISO]
- cellular response to inorganic substance [IEP]
- cellular response to molecule of bacterial origin [IEP]
- homotypic cell-cell adhesion [ISO]
- learning or memory [IDA, IMP]
- multicellular organismal response to stress [IDA]
- negative regulation of cell death [IMP]
- neuron development [IDA]
- neuron projection development [ISO]
- organ regeneration [IEP]
- peripheral nervous system axon regeneration [IEP]
- positive regulation of calcium-mediated signaling [ISO]
- positive regulation of cardiac muscle cell proliferation [IMP]
- regulation of exocyst assembly [ISO]
- regulation of sensory perception of pain [IMP]
- response to cocaine [IDA]
- response to fluoxetine [IDA]
- response to inorganic substance [IEP]
- response to lead ion [IDA]
- thalamus development [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic analysis of an interactome for long-form AMPA receptor subunits.
Glutamate receptors of the AMPA-type mediate fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity. The binding of these receptors to a variety of proteins is known to regulate their targeting to the synapse and consequently to modulate synaptic strength, as well as to modify receptor characteristics. In this study, a proteomic screening ... [more]
J. Proteome Res. Apr. 05, 2010; 9(4);1670-82 [Pubmed: 20131911]
Throughput
- High Throughput
Curated By
- BioGRID