BAIT
GRIA4
GluA4, GluR-D, GluR4
glutamate receptor, ionotropic, AMPA 4
GO Process (7)
GO Function (4)
GO Component (10)
Gene Ontology Biological Process
- ion transmembrane transport [IBA]
- ionotropic glutamate receptor signaling pathway [IDA, IMP, ISO, TAS]
- positive regulation of synaptic transmission, glutamatergic [IMP]
- regulation of synapse structure or activity [TAS]
- regulation of synaptic transmission [IMP]
- response to fungicide [IEP]
- synaptic transmission [IMP, TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [IDA, ISO]
- dendrite [IDA, IMP]
- ionotropic glutamate receptor complex [TAS]
- kainate selective glutamate receptor complex [IDA]
- neuronal cell body [IDA]
- postsynaptic density [IDA]
- postsynaptic membrane [IBA]
- synapse [IMP, ISO]
- terminal bouton [IDA]
- vesicle [ISO]
Rattus norvegicus
PREY
CNP
CNPF, CNPI, CNPII, Cnp1
2',3'-cyclic nucleotide 3' phosphodiesterase
GO Process (10)
GO Function (2)
GO Component (17)
Gene Ontology Biological Process
- adult locomotory behavior [ISO]
- aging [IEP]
- axonogenesis [ISO]
- forebrain development [IEP]
- microtubule cytoskeleton organization [IMP]
- oligodendrocyte differentiation [ISO]
- regulation of mitochondrial membrane permeability [IMP]
- response to lipopolysaccharide [IEP]
- response to toxic substance [ISO]
- substantia nigra development [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cell projection [IDA]
- cytoplasm [IDA, ISO]
- extracellular space [ISO]
- extracellular vesicular exosome [ISO]
- membrane [ISO]
- microtubule [ISO]
- microvillus [IDA]
- mitochondrial inner membrane [IDA]
- mitochondrial outer membrane [IDA]
- myelin sheath [ISO]
- myelin sheath abaxonal region [IDA]
- myelin sheath adaxonal region [IDA]
- nucleoplasm [ISO]
- nucleus [ISO]
- perinuclear region of cytoplasm [IDA]
- plasma membrane [IDA]
- pseudopodium [IDA]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic analysis of an interactome for long-form AMPA receptor subunits.
Glutamate receptors of the AMPA-type mediate fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity. The binding of these receptors to a variety of proteins is known to regulate their targeting to the synapse and consequently to modulate synaptic strength, as well as to modify receptor characteristics. In this study, a proteomic screening ... [more]
J. Proteome Res. Apr. 05, 2010; 9(4);1670-82 [Pubmed: 20131911]
Throughput
- High Throughput
Curated By
- BioGRID