BAIT
GRIA4
GluA4, GluR-D, GluR4
glutamate receptor, ionotropic, AMPA 4
GO Process (7)
GO Function (4)
GO Component (10)
Gene Ontology Biological Process
- ion transmembrane transport [IBA]
- ionotropic glutamate receptor signaling pathway [IDA, IMP, ISO, TAS]
- positive regulation of synaptic transmission, glutamatergic [IMP]
- regulation of synapse structure or activity [TAS]
- regulation of synaptic transmission [IMP]
- response to fungicide [IEP]
- synaptic transmission [IMP, TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [IDA, ISO]
- dendrite [IDA, IMP]
- ionotropic glutamate receptor complex [TAS]
- kainate selective glutamate receptor complex [IDA]
- neuronal cell body [IDA]
- postsynaptic density [IDA]
- postsynaptic membrane [IBA]
- synapse [IMP, ISO]
- terminal bouton [IDA]
- vesicle [ISO]
Rattus norvegicus
PREY
ATP1B1
ATPBS
ATPase, Na+/K+ transporting, beta 1 polypeptide
GO Process (25)
GO Function (4)
GO Component (11)
Gene Ontology Biological Process
- blastocyst development [ISO]
- cardiac muscle contraction [ISO]
- cellular calcium ion homeostasis [ISO]
- cellular potassium ion homeostasis [ISO]
- cellular sodium ion homeostasis [ISO]
- membrane repolarization [ISO]
- metal ion transport [IDA]
- positive regulation of ATP catabolic process [ISO]
- positive regulation of ATPase activity [ISO]
- positive regulation of calcium:sodium antiporter activity [ISO]
- positive regulation of potassium ion import [ISO]
- positive regulation of potassium ion transmembrane transporter activity [ISO]
- positive regulation of sodium ion export from cell [ISO]
- potassium ion import [ISO]
- potassium ion transport [IDA]
- protein localization to plasma membrane [ISO]
- protein stabilization [ISO]
- regulation of calcium ion transmembrane transport [ISO]
- regulation of cardiac muscle contraction by calcium ion signaling [ISO]
- regulation of gene expression [ISO]
- relaxation of cardiac muscle [ISO]
- response to hypoxia [IDA]
- sodium ion export from cell [ISO]
- sodium ion transmembrane transport [IDA]
- sodium ion transport [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic analysis of an interactome for long-form AMPA receptor subunits.
Glutamate receptors of the AMPA-type mediate fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity. The binding of these receptors to a variety of proteins is known to regulate their targeting to the synapse and consequently to modulate synaptic strength, as well as to modify receptor characteristics. In this study, a proteomic screening ... [more]
J. Proteome Res. Apr. 05, 2010; 9(4);1670-82 [Pubmed: 20131911]
Throughput
- High Throughput
Curated By
- BioGRID