BAIT
KDM1A
AOF2, BHC110, KDM1, LSD1, RP1-184J9.1
lysine (K)-specific demethylase 1A
GO Process (15)
GO Function (16)
GO Component (4)
Gene Ontology Biological Process
- blood coagulation [TAS]
- histone H3-K4 demethylation [IDA]
- histone H3-K9 demethylation [IDA]
- muscle cell development [ISS]
- negative regulation of DNA binding [IC]
- negative regulation of DNA damage response, signal transduction by p53 class mediator [IMP]
- negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IMP]
- negative regulation of protein binding [IMP]
- negative regulation of sequence-specific DNA binding transcription factor activity [IDA, IMP]
- negative regulation of transcription from RNA polymerase II promoter [IMP, ISS]
- negative regulation of transcription, DNA-templated [IDA]
- positive regulation of sequence-specific DNA binding transcription factor activity [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- protein demethylation [IMP]
- regulation of transcription from RNA polymerase II promoter [IMP]
Gene Ontology Molecular Function- MRF binding [IDA]
- androgen receptor binding [IDA]
- chromatin binding [IDA]
- demethylase activity [IMP]
- enzyme binding [IPI]
- flavin adenine dinucleotide binding [IDA]
- histone demethylase activity [IDA]
- histone demethylase activity (H3-K4 specific) [IDA]
- histone demethylase activity (H3-K9 specific) [IDA]
- histone demethylase activity (H3-dimethyl-K4 specific) [IDA]
- ligand-dependent nuclear receptor transcription coactivator activity [IMP]
- oxidoreductase activity [IDA]
- p53 binding [IPI]
- protein binding [IPI]
- transcription factor binding [IDA]
- transcription regulatory region DNA binding [ISS]
- MRF binding [IDA]
- androgen receptor binding [IDA]
- chromatin binding [IDA]
- demethylase activity [IMP]
- enzyme binding [IPI]
- flavin adenine dinucleotide binding [IDA]
- histone demethylase activity [IDA]
- histone demethylase activity (H3-K4 specific) [IDA]
- histone demethylase activity (H3-K9 specific) [IDA]
- histone demethylase activity (H3-dimethyl-K4 specific) [IDA]
- ligand-dependent nuclear receptor transcription coactivator activity [IMP]
- oxidoreductase activity [IDA]
- p53 binding [IPI]
- protein binding [IPI]
- transcription factor binding [IDA]
- transcription regulatory region DNA binding [ISS]
Gene Ontology Cellular Component
Homo sapiens
PREY
CCDC90B
MDS011, MDS025, CUA003
coiled-coil domain containing 90B
GO Process (0)
GO Function (0)
GO Component (1)
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human protein-protein interaction network: a resource for annotating the proteome.
Protein-protein interaction maps provide a valuable framework for a better understanding of the functional organization of the proteome. To detect interacting pairs of human proteins systematically, a protein matrix of 4456 baits and 5632 preys was screened by automated yeast two-hybrid (Y2H) interaction mating. We identified 3186 mostly novel interactions among 1705 proteins, resulting in a large, highly connected network. ... [more]
Cell Sep. 23, 2005; 122(6);957-68 [Pubmed: 16169070]
Quantitative Score
- 1.0 [Confidence Score]
Throughput
- High Throughput
Curated By
- BioGRID