BAIT
CPE
carboxypeptidase E
GO Process (6)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ROBO2
SAX3
roundabout, axon guidance receptor, homolog 2 (Drosophila)
GO Process (14)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- apoptotic process involved in luteolysis [IEP]
- axon guidance [ISS, TAS]
- axon midline choice point recognition [ISS]
- brain development [IEP]
- cellular response to hormone stimulus [IEP]
- central nervous system development [NAS]
- homophilic cell adhesion via plasma membrane adhesion molecules [IDA]
- metanephros development [ISS]
- negative regulation of negative chemotaxis [IDA]
- negative regulation of synapse assembly [ISS]
- olfactory bulb interneuron development [ISS]
- positive regulation of axonogenesis [IDA]
- retinal ganglion cell axon guidance [ISS]
- ureteric bud development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human protein-protein interaction network: a resource for annotating the proteome.
Protein-protein interaction maps provide a valuable framework for a better understanding of the functional organization of the proteome. To detect interacting pairs of human proteins systematically, a protein matrix of 4456 baits and 5632 preys was screened by automated yeast two-hybrid (Y2H) interaction mating. We identified 3186 mostly novel interactions among 1705 proteins, resulting in a large, highly connected network. ... [more]
Cell Sep. 23, 2005; 122(6);957-68 [Pubmed: 16169070]
Quantitative Score
- 1.0 [Confidence Score]
Throughput
- High Throughput
Curated By
- BioGRID