BAIT
CXCL13
ANGIE, ANGIE2, BCA-1, BCA1, BLC, BLR1L, SCYB13
chemokine (C-X-C motif) ligand 13
GO Process (22)
GO Function (8)
GO Component (2)
Gene Ontology Biological Process
- B cell chemotaxis [IDA]
- G-protein coupled receptor signaling pathway [IBA]
- activation of Rap GTPase activity [ISS]
- cell surface receptor signaling pathway [IDA]
- cell-cell signaling [IDA]
- chemokine-mediated signaling pathway [IBA]
- chronic inflammatory response [NAS]
- defense response to bacterium [IDA]
- endothelial cell chemotaxis to fibroblast growth factor [IDA]
- germinal center formation [NAS]
- immune response [IBA, IC]
- inflammatory response [IBA]
- lymphocyte chemotaxis across high endothelial venule [ISS]
- negative regulation of endothelial cell chemotaxis to fibroblast growth factor [IDA]
- positive regulation of T cell chemotaxis [IDA]
- positive regulation of cell-cell adhesion mediated by integrin [ISS]
- positive regulation of cytosolic calcium ion concentration [IDA]
- positive regulation of integrin activation [ISS]
- regulation of angiogenesis [NAS]
- regulation of cell proliferation [IBA]
- regulation of humoral immune response [NAS]
- response to lipopolysaccharide [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
EEF1G
EF1G, GIG35, PRO1608
eukaryotic translation elongation factor 1 gamma
GO Process (5)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human protein-protein interaction network: a resource for annotating the proteome.
Protein-protein interaction maps provide a valuable framework for a better understanding of the functional organization of the proteome. To detect interacting pairs of human proteins systematically, a protein matrix of 4456 baits and 5632 preys was screened by automated yeast two-hybrid (Y2H) interaction mating. We identified 3186 mostly novel interactions among 1705 proteins, resulting in a large, highly connected network. ... [more]
Cell Sep. 23, 2005; 122(6);957-68 [Pubmed: 16169070]
Quantitative Score
- 1.0 [Confidence Score]
Throughput
- High Throughput
Curated By
- BioGRID