BAIT
GNB5
GB5
guanine nucleotide binding protein (G protein), beta 5
GO Process (6)
GO Function (5)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
MVD
FP17780, MDDase, MPD
mevalonate (diphospho) decarboxylase
GO Process (9)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
- cellular protein metabolic process [TAS]
- cholesterol biosynthetic process [NAS, TAS]
- dolichol-linked oligosaccharide biosynthetic process [TAS]
- dolichyl diphosphate biosynthetic process [TAS]
- isoprenoid biosynthetic process [IDA]
- positive regulation of cell proliferation [IMP]
- post-translational protein modification [TAS]
- protein N-linked glycosylation via asparagine [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cytosol [IDA, TAS]
- peroxisome [IDA]
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human protein-protein interaction network: a resource for annotating the proteome.
Protein-protein interaction maps provide a valuable framework for a better understanding of the functional organization of the proteome. To detect interacting pairs of human proteins systematically, a protein matrix of 4456 baits and 5632 preys was screened by automated yeast two-hybrid (Y2H) interaction mating. We identified 3186 mostly novel interactions among 1705 proteins, resulting in a large, highly connected network. ... [more]
Cell Sep. 23, 2005; 122(6);957-68 [Pubmed: 16169070]
Quantitative Score
- 1.0 [Confidence Score]
Throughput
- High Throughput
Curated By
- BioGRID