BAIT
NDUFB8
ASHI, CI-ASHI, RP11-411B6.5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
GO Process (4)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PIM2
Pim-2 proto-oncogene, serine/threonine kinase
GO Process (13)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [IDA]
- cell proliferation [TAS]
- male meiosis [TAS]
- negative regulation of apoptotic process [IDA]
- negative regulation of cell proliferation [IDA]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [ISS]
- positive regulation of autophagy [ISS]
- positive regulation of transcription, DNA-templated [ISS]
- protein autophosphorylation [IBA]
- protein phosphorylation [IDA, ISS]
- protein stabilization [IMP, ISS]
- regulation of mitotic cell cycle [IBA]
- response to virus [IEP]
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human protein-protein interaction network: a resource for annotating the proteome.
Protein-protein interaction maps provide a valuable framework for a better understanding of the functional organization of the proteome. To detect interacting pairs of human proteins systematically, a protein matrix of 4456 baits and 5632 preys was screened by automated yeast two-hybrid (Y2H) interaction mating. We identified 3186 mostly novel interactions among 1705 proteins, resulting in a large, highly connected network. ... [more]
Cell Sep. 23, 2005; 122(6);957-68 [Pubmed: 16169070]
Quantitative Score
- 1.0 [Confidence Score]
Throughput
- High Throughput
Curated By
- BioGRID