BAIT
USP22
USP3L
ubiquitin specific peptidase 22
GO Process (10)
GO Function (8)
GO Component (2)
Gene Ontology Biological Process
- chromatin organization [TAS]
- embryo development [NAS]
- histone H4 acetylation [IDA]
- histone deubiquitination [IDA]
- histone ubiquitination [IDA]
- positive regulation of mitotic cell cycle [IMP]
- positive regulation of transcription, DNA-templated [IMP]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IBA]
- protein deubiquitination [IDA]
- regulation of proteasomal protein catabolic process [IBA]
Gene Ontology Molecular Function- H4 histone acetyltransferase activity [IDA]
- cysteine-type endopeptidase activity [IBA]
- enzyme binding [IPI]
- ligand-dependent nuclear receptor transcription coactivator activity [IMP]
- protein binding [IPI]
- transcription coactivator activity [IDA]
- ubiquitin thiolesterase activity [IBA]
- ubiquitin-specific protease activity [IDA, IMP]
- H4 histone acetyltransferase activity [IDA]
- cysteine-type endopeptidase activity [IBA]
- enzyme binding [IPI]
- ligand-dependent nuclear receptor transcription coactivator activity [IMP]
- protein binding [IPI]
- transcription coactivator activity [IDA]
- ubiquitin thiolesterase activity [IBA]
- ubiquitin-specific protease activity [IDA, IMP]
Gene Ontology Cellular Component
Homo sapiens
PREY
SCFD1
C14orf163, RA410, SLY1, SLY1P, STXBP1L2, FKSG23
sec1 family domain containing 1
GO Process (8)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
- cell morphogenesis [ISS]
- negative regulation of autophagic vacuole assembly [IMP]
- phagocytosis [ISS]
- post-Golgi vesicle-mediated transport [ISS]
- regulation of ER to Golgi vesicle-mediated transport [ISS]
- regulation of protein transport [IMP]
- response to toxic substance [IEP]
- retrograde vesicle-mediated transport, Golgi to ER [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human protein-protein interaction network: a resource for annotating the proteome.
Protein-protein interaction maps provide a valuable framework for a better understanding of the functional organization of the proteome. To detect interacting pairs of human proteins systematically, a protein matrix of 4456 baits and 5632 preys was screened by automated yeast two-hybrid (Y2H) interaction mating. We identified 3186 mostly novel interactions among 1705 proteins, resulting in a large, highly connected network. ... [more]
Cell Sep. 23, 2005; 122(6);957-68 [Pubmed: 16169070]
Quantitative Score
- 1.0 [Confidence Score]
Throughput
- High Throughput
Curated By
- BioGRID