BAIT
TRDMT1
DMNT2, DNMT2, MHSAIIP, PUMET, RNMT1, RP11-406H21.1
tRNA aspartic acid methyltransferase 1
GO Process (2)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
STX1A
HPC-1, P35-1, STX1, SYN1A
syntaxin 1A (brain)
GO Process (11)
GO Function (6)
GO Component (6)
Gene Ontology Biological Process
- cellular protein metabolic process [TAS]
- energy reserve metabolic process [TAS]
- glutamate secretion [TAS]
- intracellular protein transport [IBA]
- neurotransmitter secretion [TAS]
- regulation of insulin secretion [TAS]
- secretion by cell [IDA]
- small molecule metabolic process [TAS]
- synaptic transmission [TAS]
- synaptic vesicle fusion to presynaptic membrane [IBA]
- vesicle docking [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human protein-protein interaction network: a resource for annotating the proteome.
Protein-protein interaction maps provide a valuable framework for a better understanding of the functional organization of the proteome. To detect interacting pairs of human proteins systematically, a protein matrix of 4456 baits and 5632 preys was screened by automated yeast two-hybrid (Y2H) interaction mating. We identified 3186 mostly novel interactions among 1705 proteins, resulting in a large, highly connected network. ... [more]
Cell Sep. 23, 2005; 122(6);957-68 [Pubmed: 16169070]
Quantitative Score
- 2.0 [Confidence Score]
Throughput
- High Throughput
Curated By
- BioGRID