BAIT
FAM173A
C16orf24, LA16c-444G9.1
family with sequence similarity 173, member A
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
HAP1
HAP2, HIP5, HLP, hHLP1
huntingtin-associated protein 1
GO Process (14)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- anterograde axon cargo transport [ISS]
- brain development [NAS]
- negative regulation of beta-amyloid formation [ISS]
- neurotrophin TRK receptor signaling pathway [ISS]
- positive regulation of epidermal growth factor receptor signaling pathway [ISS]
- positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [ISS]
- positive regulation of neurotrophin production [ISS]
- positive regulation of nonmotile primary cilium assembly [ISS]
- positive regulation of synaptic transmission, GABAergic [ISS]
- protein localization [IMP]
- regulation of exocytosis [ISS]
- regulation of organelle transport along microtubule [ISS]
- retrograde axon cargo transport [ISS]
- synaptic transmission [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human protein-protein interaction network: a resource for annotating the proteome.
Protein-protein interaction maps provide a valuable framework for a better understanding of the functional organization of the proteome. To detect interacting pairs of human proteins systematically, a protein matrix of 4456 baits and 5632 preys was screened by automated yeast two-hybrid (Y2H) interaction mating. We identified 3186 mostly novel interactions among 1705 proteins, resulting in a large, highly connected network. ... [more]
Cell Sep. 23, 2005; 122(6);957-68 [Pubmed: 16169070]
Quantitative Score
- 2.0 [Confidence Score]
Throughput
- High Throughput
Curated By
- BioGRID