BAIT
DIS3L2
FAM6A, PRLMNS, hDIS3L2
DIS3 like 3'-5' exoribonuclease 2
GO Process (9)
GO Function (5)
GO Component (3)
Gene Ontology Biological Process
- RNA phosphodiester bond hydrolysis [IDA]
- RNA phosphodiester bond hydrolysis, exonucleolytic [IDA]
- miRNA catabolic process [IDA, ISS]
- mitotic nuclear division [IMP]
- mitotic sister chromatid separation [IMP]
- negative regulation of cell proliferation [IMP]
- nuclear-transcribed mRNA catabolic process, exonucleolytic [IMP]
- polyuridylation-dependent mRNA catabolic process [ISS]
- stem cell maintenance [ISS]
Gene Ontology Molecular Function
Homo sapiens
PREY
VIM
CTRCT30, HEL113, RP11-124N14.1
vimentin
GO Process (4)
GO Function (7)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human protein-protein interaction network: a resource for annotating the proteome.
Protein-protein interaction maps provide a valuable framework for a better understanding of the functional organization of the proteome. To detect interacting pairs of human proteins systematically, a protein matrix of 4456 baits and 5632 preys was screened by automated yeast two-hybrid (Y2H) interaction mating. We identified 3186 mostly novel interactions among 1705 proteins, resulting in a large, highly connected network. ... [more]
Cell Sep. 23, 2005; 122(6);957-68 [Pubmed: 16169070]
Quantitative Score
- 2.0 [Confidence Score]
Throughput
- High Throughput
Curated By
- BioGRID