BAIT
ACOT8
HNAACTE, PTE-1, PTE-2, PTE1, PTE2, hACTE-III, hTE, RP3-337O18.2
acyl-CoA thioesterase 8
GO Process (10)
GO Function (5)
GO Component (1)
Gene Ontology Biological Process
- acyl-CoA metabolic process [IDA]
- alpha-linolenic acid metabolic process [TAS]
- bile acid biosynthetic process [TAS]
- bile acid metabolic process [TAS]
- cellular lipid metabolic process [TAS]
- dicarboxylic acid catabolic process [IDA]
- fatty acid beta-oxidation using acyl-CoA oxidase [TAS]
- peroxisome fission [IDA]
- small molecule metabolic process [TAS]
- unsaturated fatty acid metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- peroxisomal matrix [IDA, IMP, TAS]
Homo sapiens
PREY
P4HA3
UNQ711/PRO1374
prolyl 4-hydroxylase, alpha polypeptide III
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A reference map of the human binary protein interactome.
Global insights into cellular organization and genome function require comprehensive understanding of the interactome networks that mediate genotype-phenotype relationships1,2. Here we present a human 'all-by-all' reference interactome map of human binary protein interactions, or 'HuRI'. With approximately 53,000 protein-protein interactions, HuRI has approximately four times as many such interactions as there are high-quality curated interactions from small-scale studies. The integration ... [more]
Nature Apr. 01, 2020; 580(7803);402-408 [Pubmed: 32296183]
Throughput
- High Throughput
Additional Notes
- This human reference interactome (HuRI) was generated by performing nine two-hybrid screens with the high confidence interactions determined by pairwise verification by quadruplicate retesting and sequence confirmation. This HI-III-20 dataset contains over 52,000 PPIs involving more than 8,000 proteins.
Curated By
- BioGRID