BAIT
DIS3
2810028N01Rik, EXOSC11, KIAA1008, RRP44, dis3p, RP11-342J4.3
DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
GO Process (11)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
- CUT catabolic process [IMP]
- RNA metabolic process [TAS]
- RNA phosphodiester bond hydrolysis, exonucleolytic [IMP]
- exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [TAS]
- nucleic acid phosphodiester bond hydrolysis [IMP]
- positive regulation of GTPase activity [IDA]
- rRNA catabolic process [IMP]
- rRNA processing [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ZBTB17
MIZ-1, ZNF151, ZNF60, pHZ-67, RP1-134O19.2
zinc finger and BTB domain containing 17
GO Process (4)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction framework for human mRNA degradation.
The degradation of mRNA is an important regulatory step in the control of gene expression. However, mammalian RNA decay pathways remain poorly characterized. To provide a framework for studying mammalian RNA decay, a two-hybrid protein interaction map was generated using 54 constructs from 38 human proteins predicted to function in mRNA decay. The results provide evidence for interactions between many ... [more]
Genome Res. Jul. 01, 2004; 14(7);1315-23 [Pubmed: 15231747]
Throughput
- High Throughput
Curated By
- BioGRID