BAIT
ZEB2
HSPC082, SIP-1, SIP1, SMADIP1, ZFHX1B, HRIHFB2411
zinc finger E-box binding homeobox 2
GO Process (8)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
- developmental pigmentation [ISS]
- melanocyte migration [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- nervous system development [NAS]
- positive regulation of melanin biosynthetic process [IC]
- positive regulation of melanocyte differentiation [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- regulation of melanosome organization [ISS]
Gene Ontology Molecular Function
Homo sapiens
PREY
COPS6
CSN6, MOV34-34KD
COP9 signalosome subunit 6
GO Process (1)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human protein-protein interaction network: a resource for annotating the proteome.
Protein-protein interaction maps provide a valuable framework for a better understanding of the functional organization of the proteome. To detect interacting pairs of human proteins systematically, a protein matrix of 4456 baits and 5632 preys was screened by automated yeast two-hybrid (Y2H) interaction mating. We identified 3186 mostly novel interactions among 1705 proteins, resulting in a large, highly connected network. ... [more]
Cell Sep. 23, 2005; 122(6);957-68 [Pubmed: 16169070]
Quantitative Score
- 2.0 [Confidence Score]
Throughput
- High Throughput
Curated By
- BioGRID