BAIT
CREB1
CREB
cAMP responsive element binding protein 1
GO Process (35)
GO Function (11)
GO Component (3)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- MyD88-dependent toll-like receptor signaling pathway [TAS]
- MyD88-independent toll-like receptor signaling pathway [TAS]
- Notch signaling pathway [TAS]
- TRIF-dependent toll-like receptor signaling pathway [TAS]
- activation of phospholipase C activity [TAS]
- axon guidance [TAS]
- circadian rhythm [ISS]
- epidermal growth factor receptor signaling pathway [TAS]
- fibroblast growth factor receptor signaling pathway [TAS]
- innate immune response [TAS]
- negative regulation of transcription by competitive promoter binding [IDA]
- neurotrophin TRK receptor signaling pathway [TAS]
- phosphatidylinositol-mediated signaling [TAS]
- positive regulation of fat cell differentiation [ISS]
- positive regulation of lipid biosynthetic process [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [ISS]
- protein phosphorylation [IDA]
- protein stabilization [ISS]
- response to glucagon [ISS]
- response to organic substance [IDA]
- signal transduction [TAS]
- stress-activated MAPK cascade [TAS]
- synaptic transmission [TAS]
- toll-like receptor 10 signaling pathway [TAS]
- toll-like receptor 2 signaling pathway [TAS]
- toll-like receptor 3 signaling pathway [TAS]
- toll-like receptor 4 signaling pathway [TAS]
- toll-like receptor 5 signaling pathway [TAS]
- toll-like receptor 9 signaling pathway [TAS]
- toll-like receptor TLR1:TLR2 signaling pathway [TAS]
- toll-like receptor TLR6:TLR2 signaling pathway [TAS]
- toll-like receptor signaling pathway [TAS]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- RNA polymerase II activating transcription factor binding [IPI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IC]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription [IDA]
- cAMP response element binding [IDA]
- enzyme binding [IPI]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription cofactor activity [TAS]
- RNA polymerase II activating transcription factor binding [IPI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IC]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription [IDA]
- cAMP response element binding [IDA]
- enzyme binding [IPI]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription cofactor activity [TAS]
Gene Ontology Cellular Component
Homo sapiens
PREY
VIM
CTRCT30, HEL113, RP11-124N14.1
vimentin
GO Process (4)
GO Function (7)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human protein-protein interaction network: a resource for annotating the proteome.
Protein-protein interaction maps provide a valuable framework for a better understanding of the functional organization of the proteome. To detect interacting pairs of human proteins systematically, a protein matrix of 4456 baits and 5632 preys was screened by automated yeast two-hybrid (Y2H) interaction mating. We identified 3186 mostly novel interactions among 1705 proteins, resulting in a large, highly connected network. ... [more]
Cell Sep. 23, 2005; 122(6);957-68 [Pubmed: 16169070]
Quantitative Score
- 3.0 [Confidence Score]
Throughput
- High Throughput
Curated By
- BioGRID