BAIT
FXYD6
UNQ521/PRO1056
FXYD domain containing ion transport regulator 6
GO Process (2)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
TLE1
ESG, ESG1, GRG1, RP11-203D19.1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
GO Process (9)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
- Notch signaling pathway [TAS]
- multicellular organismal development [TAS]
- negative regulation of I-kappaB kinase/NF-kappaB signaling [IDA]
- negative regulation of Wnt signaling pathway [NAS]
- negative regulation of anoikis [IMP]
- negative regulation of transcription, DNA-templated [IDA]
- organ morphogenesis [TAS]
- positive regulation of gene expression [IMP]
- signal transduction [TAS]
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human protein-protein interaction network: a resource for annotating the proteome.
Protein-protein interaction maps provide a valuable framework for a better understanding of the functional organization of the proteome. To detect interacting pairs of human proteins systematically, a protein matrix of 4456 baits and 5632 preys was screened by automated yeast two-hybrid (Y2H) interaction mating. We identified 3186 mostly novel interactions among 1705 proteins, resulting in a large, highly connected network. ... [more]
Cell Sep. 23, 2005; 122(6);957-68 [Pubmed: 16169070]
Quantitative Score
- 3.0 [Confidence Score]
Throughput
- High Throughput
Curated By
- BioGRID