BAIT
OPRD1
OPRD
opioid receptor, delta 1
GO Process (16)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [IDA]
- G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [TAS]
- cellular response to hypoxia [IDA]
- cellular response to toxic substance [IDA]
- immune response [TAS]
- negative regulation of gene expression [IDA]
- negative regulation of protein oligomerization [IDA]
- neuropeptide signaling pathway [IBA]
- opioid receptor signaling pathway [IMP]
- phospholipase C-activating G-protein coupled receptor signaling pathway [ISS]
- positive regulation of CREB transcription factor activity [IC]
- positive regulation of peptidyl-serine phosphorylation [IDA]
- protein import into nucleus, translocation [IDA]
- regulation of mitochondrial membrane potential [IDA]
- sensory perception of pain [IBA]
- synaptic transmission [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SMAGP
hSMAGP
small cell adhesion glycoprotein
GO Process (0)
GO Function (0)
GO Component (3)
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A reference map of the human binary protein interactome.
Global insights into cellular organization and genome function require comprehensive understanding of the interactome networks that mediate genotype-phenotype relationships1,2. Here we present a human 'all-by-all' reference interactome map of human binary protein interactions, or 'HuRI'. With approximately 53,000 protein-protein interactions, HuRI has approximately four times as many such interactions as there are high-quality curated interactions from small-scale studies. The integration ... [more]
Nature Apr. 01, 2020; 580(7803);402-408 [Pubmed: 32296183]
Throughput
- High Throughput
Additional Notes
- This human reference interactome (HuRI) was generated by performing nine two-hybrid screens with the high confidence interactions determined by pairwise verification by quadruplicate retesting and sequence confirmation. This HI-III-20 dataset contains over 52,000 PPIs involving more than 8,000 proteins.
Curated By
- BioGRID