BAIT
TIMP1
CLGI, EPA, EPO, HCI, TIMP, RP1-230G1.3
TIMP metallopeptidase inhibitor 1
GO Process (11)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- blood coagulation [TAS]
- extracellular matrix disassembly [TAS]
- extracellular matrix organization [TAS]
- negative regulation of endopeptidase activity [IDA]
- negative regulation of membrane protein ectodomain proteolysis [IDA]
- negative regulation of metalloenzyme activity [IDA]
- negative regulation of trophoblast cell migration [IMP]
- platelet activation [TAS]
- platelet degranulation [TAS]
- positive regulation of cell proliferation [IDA]
- regulation of integrin-mediated signaling pathway [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
EEF1B2
EEF1B, EEF1B1, EF1B
eukaryotic translation elongation factor 1 beta 2
GO Process (4)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human protein-protein interaction network: a resource for annotating the proteome.
Protein-protein interaction maps provide a valuable framework for a better understanding of the functional organization of the proteome. To detect interacting pairs of human proteins systematically, a protein matrix of 4456 baits and 5632 preys was screened by automated yeast two-hybrid (Y2H) interaction mating. We identified 3186 mostly novel interactions among 1705 proteins, resulting in a large, highly connected network. ... [more]
Cell Sep. 23, 2005; 122(6);957-68 [Pubmed: 16169070]
Quantitative Score
- 4.0 [Confidence Score]
Throughput
- High Throughput
Curated By
- BioGRID