BAIT
SRR
ILV1, ISO1
serine racemase
GO Process (7)
GO Function (10)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function- ATP binding [IDA, ISS]
- L-serine ammonia-lyase activity [IDA]
- PDZ domain binding [IPI]
- calcium ion binding [ISS]
- glycine binding [ISS]
- magnesium ion binding [IDA]
- protein homodimerization activity [IDA, IPI]
- pyridoxal phosphate binding [IDA, ISS]
- serine racemase activity [IDA]
- threonine racemase activity [ISS]
- ATP binding [IDA, ISS]
- L-serine ammonia-lyase activity [IDA]
- PDZ domain binding [IPI]
- calcium ion binding [ISS]
- glycine binding [ISS]
- magnesium ion binding [IDA]
- protein homodimerization activity [IDA, IPI]
- pyridoxal phosphate binding [IDA, ISS]
- serine racemase activity [IDA]
- threonine racemase activity [ISS]
Gene Ontology Cellular Component
Homo sapiens
PREY
SRR
ILV1, ISO1
serine racemase
GO Process (7)
GO Function (10)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function- ATP binding [IDA, ISS]
- L-serine ammonia-lyase activity [IDA]
- PDZ domain binding [IPI]
- calcium ion binding [ISS]
- glycine binding [ISS]
- magnesium ion binding [IDA]
- protein homodimerization activity [IDA, IPI]
- pyridoxal phosphate binding [IDA, ISS]
- serine racemase activity [IDA]
- threonine racemase activity [ISS]
- ATP binding [IDA, ISS]
- L-serine ammonia-lyase activity [IDA]
- PDZ domain binding [IPI]
- calcium ion binding [ISS]
- glycine binding [ISS]
- magnesium ion binding [IDA]
- protein homodimerization activity [IDA, IPI]
- pyridoxal phosphate binding [IDA, ISS]
- serine racemase activity [IDA]
- threonine racemase activity [ISS]
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A reference map of the human binary protein interactome.
Global insights into cellular organization and genome function require comprehensive understanding of the interactome networks that mediate genotype-phenotype relationships1,2. Here we present a human 'all-by-all' reference interactome map of human binary protein interactions, or 'HuRI'. With approximately 53,000 protein-protein interactions, HuRI has approximately four times as many such interactions as there are high-quality curated interactions from small-scale studies. The integration ... [more]
Nature Apr. 01, 2020; 580(7803);402-408 [Pubmed: 32296183]
Throughput
- High Throughput
Additional Notes
- This human reference interactome (HuRI) was generated by performing nine two-hybrid screens with the high confidence interactions determined by pairwise verification by quadruplicate retesting and sequence confirmation. This HI-III-20 dataset contains over 52,000 PPIs involving more than 8,000 proteins.
Related interactions
Curated By
- BioGRID