BAIT
ETFDH
ETFQO, MADD
electron-transferring-flavoprotein dehydrogenase
GO Process (6)
GO Function (8)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function- 4 iron, 4 sulfur cluster binding [IDA]
- electron carrier activity [IDA]
- electron-transferring-flavoprotein dehydrogenase activity [IDA]
- flavin adenine dinucleotide binding [ISS]
- oxidoreductase activity [IDA]
- oxidoreductase activity, oxidizing metal ions with flavin as acceptor [ISS]
- quinone binding [IDA]
- ubiquinone binding [IDA]
- 4 iron, 4 sulfur cluster binding [IDA]
- electron carrier activity [IDA]
- electron-transferring-flavoprotein dehydrogenase activity [IDA]
- flavin adenine dinucleotide binding [ISS]
- oxidoreductase activity [IDA]
- oxidoreductase activity, oxidizing metal ions with flavin as acceptor [ISS]
- quinone binding [IDA]
- ubiquinone binding [IDA]
Gene Ontology Cellular Component
Homo sapiens
PREY
KRTAP13-2
KAP13-2
keratin associated protein 13-2
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A reference map of the human binary protein interactome.
Global insights into cellular organization and genome function require comprehensive understanding of the interactome networks that mediate genotype-phenotype relationships1,2. Here we present a human 'all-by-all' reference interactome map of human binary protein interactions, or 'HuRI'. With approximately 53,000 protein-protein interactions, HuRI has approximately four times as many such interactions as there are high-quality curated interactions from small-scale studies. The integration ... [more]
Nature Apr. 01, 2020; 580(7803);402-408 [Pubmed: 32296183]
Throughput
- High Throughput
Additional Notes
- This human reference interactome (HuRI) was generated by performing nine two-hybrid screens with the high confidence interactions determined by pairwise verification by quadruplicate retesting and sequence confirmation. This HI-III-20 dataset contains over 52,000 PPIs involving more than 8,000 proteins.
Curated By
- BioGRID