BAIT
XIAP
API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3, RP1-315G1.5
X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
GO Process (17)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- apoptotic process [TAS]
- cellular response to DNA damage stimulus [IEP]
- copper ion homeostasis [TAS]
- inhibition of cysteine-type endopeptidase activity involved in apoptotic process [IBA]
- intrinsic apoptotic signaling pathway [TAS]
- negative regulation of apoptotic process [IMP]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- positive regulation of canonical Wnt signaling pathway [IMP]
- positive regulation of protein linear polyubiquitination [IDA]
- positive regulation of protein ubiquitination [IDA]
- protein ubiquitination [IDA]
- regulation of BMP signaling pathway [TAS]
- regulation of cell proliferation [TAS]
- regulation of inflammatory response [TAS]
- regulation of innate immune response [TAS]
- regulation of nucleotide-binding oligomerization domain containing signaling pathway [TAS]
- spindle assembly involved in mitosis [IBA]
Gene Ontology Molecular Function
Homo sapiens
PREY
PCBP1
HEL-S-85, HNRPE1, HNRPX, hnRNP-E1, hnRNP-X
poly(rC) binding protein 1
GO Process (3)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The X-linked inhibitor of apoptosis protein (XIAP) is involved in melanoma invasion by regulating cell migration and survival.
The X-linked inhibitor of apoptosis (XIAP) is a potent cellular inhibitor of apoptosis, based on its unique capability to bind and to inhibit caspases. However, XIAP is also involved in a number of additional cellular activities independent of its caspase inhibitory function. The aim of this study was to investigate whether modulation of XIAP expression affects apoptosis-independent functions of XIAP ... [more]
Cell Oncol (Dordr) Jun. 01, 2019; 42(3);319-329 [Pubmed: 30778852]
Throughput
- High Throughput
Curated By
- BioGRID