Phenotypic Enhancement

A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.

Publication

Interactions of neuropeptide Y, hypocretin-I (orexin A) and melanin-concentrating hormone on feeding in rats.

Sahu A

Amongst various neuropeptidergic systems, neuropeptide Y (NPY), hypocretin-1 and melanin-concentrating hormone (MCH) producing neurons have been shown to play an important role in the regulation of food intake and body weight. All of these neuropeptides are orexigenic signals and recent evidence suggests the existence of morphological connections between these neuronal systems in the hypothalamus. However, the functional interactions between these ... [more]

Brain Res. Jul. 19, 2002; 944(1);232-8 [Pubmed: 12106685]

Throughput

  • Low Throughput

Curated By

  • BioGRID