BAIT
ZBTB7B
Thpok, Zfp67, c-Krox
zinc finger and BTB domain containing 7B
GO Process (5)
GO Function (6)
GO Component (2)
Gene Ontology Biological Process
- positive regulation of gene expression [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of CD4-positive, alpha-beta T cell differentiation [IMP]
- regulation of CD8-positive, alpha-beta T cell differentiation [IMP]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
Gene Ontology Cellular Component
- nucleoplasm [ISO]
- nucleus [ISO]
Mus musculus
PREY
AURKA
AIRK1, ARK-1, AU019385, AW539821, Ark1, Aurora-A, Ayk1, IAK, IAK1, Stk6
aurora kinase A
GO Process (23)
GO Function (7)
GO Component (16)
Gene Ontology Biological Process
- anterior/posterior axis specification [IMP]
- centrosome localization [IMP]
- centrosome organization [IGI]
- histone-serine phosphorylation [IMP]
- meiotic nuclear division [IMP]
- meiotic spindle organization [IMP]
- microtubule cytoskeleton organization [IGI]
- mitotic cell cycle [IMP]
- mitotic centrosome separation [IGI, IMP]
- mitotic nuclear division [IMP]
- mitotic spindle organization [IMP]
- negative regulation of apoptotic process [IMP]
- negative regulation of protein binding [ISO]
- negative regulation of spindle checkpoint [IMP]
- neuron projection extension [IGI]
- positive regulation of oocyte maturation [IMP]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [IMP]
- protein localization to centrosome [IMP]
- protein phosphorylation [IBA, IGI, ISO]
- regulation of cytokinesis [IBA]
- regulation of protein stability [ISO]
- spindle assembly involved in female meiosis I [IMP]
- spindle stabilization [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- axon hillock [IDA]
- centrosome [IDA, ISO]
- chromosome passenger complex [IBA]
- condensed nuclear chromosome, centromeric region [IBA]
- germinal vesicle [IDA]
- meiotic spindle [IDA]
- microtubule cytoskeleton [ISO]
- microtubule organizing center [IGI]
- mitotic spindle [IDA]
- nucleus [ISO]
- perinuclear region of cytoplasm [ISO]
- pronucleus [IDA]
- spindle [ISO]
- spindle microtubule [IBA, ISO]
- spindle midzone [IBA]
- spindle pole centrosome [IBA, ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.
GAGA associated factor (GAF) is a sequence-specific DNA binding transcription factor that is evolutionarily conserved from flies to humans. Emerging evidence shows a context-dependent function of vertebrate GAF (vGAF, a.k.a. ThPOK) in multiple processes like gene activation, repression, and enhancer-blocking. We hypothesize that context-dependent interaction of vGAF with a diverse set of proteins forms the basis for the multifunctional nature ... [more]
J. Biosci. Feb. 27, 2020; 45(); [Pubmed: 32098917]
Throughput
- High Throughput
Curated By
- BioGRID