BAIT
ZBTB7B
Thpok, Zfp67, c-Krox
zinc finger and BTB domain containing 7B
GO Process (5)
GO Function (6)
GO Component (2)
Gene Ontology Biological Process
- positive regulation of gene expression [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of CD4-positive, alpha-beta T cell differentiation [IMP]
- regulation of CD8-positive, alpha-beta T cell differentiation [IMP]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
Gene Ontology Cellular Component
- nucleoplasm [ISO]
- nucleus [ISO]
Mus musculus
PREY
PPP1CC
PP-1G, PP1, dis2m1
protein phosphatase 1, catalytic subunit, gamma isoform
GO Process (3)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.
GAGA associated factor (GAF) is a sequence-specific DNA binding transcription factor that is evolutionarily conserved from flies to humans. Emerging evidence shows a context-dependent function of vertebrate GAF (vGAF, a.k.a. ThPOK) in multiple processes like gene activation, repression, and enhancer-blocking. We hypothesize that context-dependent interaction of vGAF with a diverse set of proteins forms the basis for the multifunctional nature ... [more]
J. Biosci. Feb. 27, 2020; 45(); [Pubmed: 32098917]
Throughput
- High Throughput
Curated By
- BioGRID