BAIT
FER
FerT, PPP1R74, Pe1Fe10, Pe1Fe13, Pe1Fe3, Pe1Fe6, TYK3
fer (fps/fes related) tyrosine kinase
GO Process (39)
GO Function (5)
GO Component (9)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [IBA, ISS]
- Kit signaling pathway [ISS]
- actin cytoskeleton reorganization [ISS]
- cell adhesion [IBA]
- cell differentiation [IBA]
- cell proliferation [IMP]
- cell-cell adhesion mediated by cadherin [ISS]
- cellular response to insulin stimulus [ISS]
- cellular response to macrophage colony-stimulating factor stimulus [IMP]
- cellular response to reactive oxygen species [ISS]
- chemotaxis [IBA]
- cytokine-mediated signaling pathway [IMP]
- diapedesis [ISS]
- extracellular matrix-cell signaling [ISS]
- innate immune response [IBA]
- insulin receptor signaling pathway via phosphatidylinositol 3-kinase [ISS]
- interleukin-6-mediated signaling pathway [IMP]
- intracellular signal transduction [TAS]
- microtubule cytoskeleton organization [IMP]
- mitotic cell cycle [IMP]
- negative regulation of mast cell activation involved in immune response [ISS]
- peptidyl-tyrosine autophosphorylation [IBA]
- peptidyl-tyrosine phosphorylation [IDA]
- platelet-derived growth factor receptor signaling pathway [ISS, TAS]
- positive regulation of NF-kappaB transcription factor activity [IMP]
- positive regulation of actin filament polymerization [IMP]
- positive regulation of cell migration [IMP]
- positive regulation of cell proliferation [TAS]
- protein autophosphorylation [IDA]
- protein phosphorylation [TAS]
- regulation of cell proliferation [IBA]
- regulation of epidermal growth factor receptor signaling pathway [IMP]
- regulation of lamellipodium assembly [IDA]
- regulation of mast cell degranulation [IBA]
- regulation of protein phosphorylation [ISS]
- response to lipopolysaccharide [ISS]
- response to platelet-derived growth factor [ISS]
- substrate adhesion-dependent cell spreading [ISS]
- tyrosine phosphorylation of Stat3 protein [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
DNM3
Dyna III, RP1-106H8.3
dynamin 3
GO Process (4)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Growth factor-dependent phosphorylation of the actin-binding protein cortactin is mediated by the cytoplasmic tyrosine kinase FER.
Previous characterization of the nonreceptor tyrosine kinase FER identified a tight physical association with the catenin pp120 and led to the suggestion that FER may be involved in cell-cell signaling. To further understand the function of FER, we have continued our analyses of the interaction of FER with pp120 and other proteins. The majority of FER is localized to the ... [more]
J. Biol. Chem. Sep. 04, 1998; 273(36);23542-8 [Pubmed: 9722593]
Throughput
- Low Throughput
Curated By
- BioGRID