BAIT
WASF3
Brush-1, SCAR3, WAVE3, RP11-496O3.2
WAS protein family, member 3
GO Process (4)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
ACTR3
ARP3
ARP3 actin-related protein 3 homolog (yeast)
GO Process (5)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex.
WAVE/SCAR protein was identified as a protein which has similarity to WASP and N-WASP, especially in its C terminal. Recently, WAVE/SCAR protein has been shown to cooperate with the Arp2/3 complex, a nucleation core for actin polymerization in vitro. However, in spite of its general function, WAVE/SCAR expression is mainly restricted to the brain, suggesting the existence of related molecule(s). ... [more]
Biochem. Biophys. Res. Commun. Jun. 24, 1999; 260(1);296-302 [Pubmed: 10381382]
Throughput
- Low Throughput
Curated By
- BioGRID