BAIT
TTF2
HuF2, ZGRF6
transcription termination factor, RNA polymerase II
GO Process (3)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
DCP1A
HSA275986, Nbla00360, SMAD4IP1, SMIF
decapping mRNA 1A
GO Process (5)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
hLodestar/HuF2 interacts with CDC5L and is involved in pre-mRNA splicing.
hLodestar/HuF2 belongs to the SNF2 family of proteins. This family of proteins has been shown to play a critical role in altering protein-DNA interactions in a variety of cellular contexts. We have identified an unexpected interaction between hLodestar/HuF2 and CDC5L in both the yeast two-hybrid system and HeLa nuclear extract. CDC5L is a well-characterized pre-mRNA splicing factor in yeast and ... [more]
Biochem. Biophys. Res. Commun. Sep. 05, 2003; 308(4);793-801 [Pubmed: 12927788]
Throughput
- Low Throughput
Curated By
- BioGRID