BAIT
HNRNPD
AUF1, AUF1A, HNRPD, P37, hnRNPD0
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
GO Process (12)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
- RNA catabolic process [TAS]
- RNA metabolic process [TAS]
- RNA processing [TAS]
- RNA splicing [TAS]
- circadian regulation of translation [IMP]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- mRNA splicing, via spliceosome [TAS]
- positive regulation of transcription, DNA-templated [NAS]
- positive regulation of translation [IMP]
- regulation of circadian rhythm [IMP]
- regulation of transcription, DNA-templated [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
LRP8
APOER2, HSZ75190, LRP-8, MCI1, RP5-1024G6.8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
GO Process (18)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
- ammon gyrus development [ISS]
- blood coagulation [TAS]
- cytokine-mediated signaling pathway [NAS]
- endocytosis [IDA]
- lipid metabolic process [NAS]
- negative regulation of transcription from RNA polymerase II promoter [ISS]
- phototransduction, visible light [TAS]
- positive regulation of CREB transcription factor activity [ISS]
- positive regulation of dendrite development [ISS]
- positive regulation of dendritic spine morphogenesis [ISS]
- positive regulation of peptidyl-tyrosine phosphorylation [ISS]
- positive regulation of protein tyrosine kinase activity [ISS]
- proteolysis [NAS]
- receptor-mediated endocytosis [IDA]
- reelin-mediated signaling pathway [ISS]
- regulation of synaptic transmission [ISS]
- retinoid metabolic process [TAS]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Nuclear heterogeneous nuclear ribonucleoprotein D is associated with poor prognosis and interactome analysis reveals its novel binding partners in oral cancer.
Post-transcriptional regulation by heterogeneous ribonucleoproteins (hnRNPs) is an important regulatory paradigm in cancer development. Our proteomic analysis revealed hnRNPD overexpression in oral dysplasia as compared with normal mucosa; its role in oral carcinogenesis remains unknown. Here in we determined the hnRNPD associated protein networks and its clinical significance in oral squamous cell carcinoma (OSCC).Immunoprecipitation (IP) followed by tandem mass spectrometry ... [more]
J Transl Med Aug. 30, 2015; 13();285 [Pubmed: 26318153]
Throughput
- High Throughput
Curated By
- BioGRID