HBB
Gene Ontology Biological Process
- bicarbonate transport [TAS]
- blood coagulation [TAS]
- hydrogen peroxide catabolic process [IDA]
- nitric oxide transport [NAS]
- oxidation-reduction process [IDA]
- oxygen transport [NAS, TAS]
- platelet aggregation [IMP]
- positive regulation of cell death [IDA]
- positive regulation of nitric oxide biosynthetic process [NAS]
- protein heterooligomerization [IDA]
- renal absorption [IMP]
- response to hydrogen peroxide [IDA]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
HBA1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Co-crystal Structure
Interaction directly demonstrated at the atomic level by X-ray crystallography. Also used for NMR or Electron Microscopy (EM) structures. If there is no obvious bait-hit directionality to the interaction involving 3 or more proteins, then the co-crystallized proteins should be listed as a complex.
Publication
Structure of human oxyhaemoglobin at 2.1 A resolution.
The structure of human oxyhaemoglobin was determined by single crystal X-ray analysis at 2.1 A resolution. Data were collected on an Arndt-Wonacott camera at -2 degrees C. The structure was refined to an R factor of 0.223 by the Jack-Levitt method, starting from Baldwin's model of human carbon monoxide haemoglobin. The active sites in the alpha and beta subunit are ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| HBA1 HBB | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | 2745485 | |
| HBA1 HBB | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | 2 | BioGRID | - |
Curated By
- BioGRID