SNX27
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ATP7A
Gene Ontology Biological Process
- T-helper cell differentiation [ISS]
- blood vessel development [ISS]
- blood vessel remodeling [ISS]
- cartilage development [ISS]
- catecholamine metabolic process [ISS]
- cellular copper ion homeostasis [IMP]
- central nervous system neuron development [ISS]
- cerebellar Purkinje cell differentiation [ISS]
- collagen fibril organization [ISS]
- copper ion export [ISS]
- copper ion import [ISS]
- copper ion transport [IMP]
- detoxification of copper ion [ISS]
- dopamine metabolic process [ISS]
- elastic fiber assembly [ISS]
- elastin biosynthetic process [ISS]
- epinephrine metabolic process [ISS]
- extracellular matrix organization [ISS]
- hair follicle morphogenesis [ISS]
- ion transmembrane transport [TAS]
- locomotory behavior [ISS]
- lung alveolus development [ISS]
- mitochondrion organization [ISS]
- negative regulation of metalloenzyme activity [ISS]
- neuron projection morphogenesis [ISS]
- norepinephrine metabolic process [ISS]
- peptidyl-lysine modification [ISS]
- pigmentation [ISS]
- positive regulation of catalytic activity [ISS]
- positive regulation of metalloenzyme activity [ISS]
- positive regulation of oxidoreductase activity [IDA]
- pyramidal neuron development [ISS]
- regulation of oxidative phosphorylation [ISS]
- removal of superoxide radicals [ISS]
- serotonin metabolic process [ISS]
- skin development [ISS]
- transmembrane transport [TAS]
- tryptophan metabolic process [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Regulation of the endosomal SNX27-retromer by OTULIN.
OTULINĀ (OTU Deubiquitinase With Linear Linkage Specificity) specifically hydrolyzes methionine1 (Met1)-linked ubiquitin chains conjugated by LUBAC (linear ubiquitin chain assembly complex). Here we report on the mass spectrometric identification of the OTULIN interactor SNX27 (sorting nexin 27), an adaptor of the endosomal retromer complex responsible for protein recycling to the cell surface. The C-terminal PDZ-binding motif (PDZbm) in OTULIN associates with ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID