Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
gamma-Syntrophin scaffolding is spatially and functionally distinct from that of the alpha/beta syntrophins.
The syntrophins are a family of scaffolding proteins with multiple protein interaction domains that link signaling proteins to dystrophin family members. Each of the three most characterized syntrophins (alpha, beta1, beta2) contains a PDZ domain that binds a unique set of signaling proteins including kinases, ion and water channels, and neuronal nitric oxide synthase (nNOS). The PDZ domains of the ... [more]
Exp. Cell Res. Oct. 01, 2006; 312(16);3084-95 [Pubmed: 16857187]
Throughput
- Low Throughput
Curated By
- BioGRID