BAIT
SNTB2
Snt2
syntrophin, basic 2
GO Process (0)
GO Function (2)
GO Component (5)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
NOS1
2310005C01Rik, NO, NOS-I, Nos-1, bNOS, nNOS
nitric oxide synthase 1, neuronal
GO Process (40)
GO Function (15)
GO Component (20)
Gene Ontology Biological Process
- arginine catabolic process [ISO]
- behavioral response to cocaine [ISO]
- cellular response to epinephrine stimulus [ISO]
- cellular response to growth factor stimulus [IMP]
- cellular response to mechanical stimulus [ISO]
- exogenous drug catabolic process [IMP]
- multicellular organismal response to stress [ISO]
- negative regulation of apoptotic process [ISO]
- negative regulation of blood pressure [IBA, ISO]
- negative regulation of calcium ion transport [IMP]
- negative regulation of cell proliferation [ISO]
- negative regulation of cytosolic calcium ion concentration [ISO]
- negative regulation of heart contraction [ISO]
- negative regulation of hydrolase activity [IMP]
- negative regulation of insulin secretion [ISO]
- negative regulation of peptidyl-serine phosphorylation [ISO]
- negative regulation of potassium ion transport [IMP]
- negative regulation of serotonin uptake [IDA]
- negative regulation of vasoconstriction [ISO]
- nitric oxide biosynthetic process [IDA, ISO]
- nitric oxide mediated signal transduction [IBA, ISO]
- oxidation-reduction process [IBA]
- peptidyl-cysteine S-nitrosylation [IDA, ISO]
- positive regulation of adrenergic receptor signaling pathway involved in heart process [IMP]
- positive regulation of guanylate cyclase activity [IBA]
- positive regulation of histone acetylation [IMP]
- positive regulation of long-term synaptic potentiation [ISO]
- positive regulation of neuron death [ISO]
- positive regulation of sodium ion transmembrane transport [ISO]
- positive regulation of the force of heart contraction [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of transcription, DNA-templated [IMP]
- positive regulation of vasodilation [IBA, ISO]
- regulation of heart contraction [ISO]
- regulation of sensory perception of pain [ISO]
- regulation of sodium ion transport [IMP]
- response to estrogen [ISO]
- response to heat [ISO]
- response to peptide hormone [ISO]
- striated muscle contraction [IMP]
Gene Ontology Molecular Function- ATPase binding [ISO]
- FMN binding [ISO]
- NADP binding [ISO]
- NADPH-hemoprotein reductase activity [IBA]
- cadmium ion binding [ISO]
- calmodulin binding [ISO]
- enzyme binding [ISO]
- flavin adenine dinucleotide binding [ISO]
- heme binding [ISO]
- ion channel binding [ISO]
- nitric-oxide synthase activity [IDA, ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- scaffold protein binding [ISO]
- sodium channel regulator activity [ISO]
- ATPase binding [ISO]
- FMN binding [ISO]
- NADP binding [ISO]
- NADPH-hemoprotein reductase activity [IBA]
- cadmium ion binding [ISO]
- calmodulin binding [ISO]
- enzyme binding [ISO]
- flavin adenine dinucleotide binding [ISO]
- heme binding [ISO]
- ion channel binding [ISO]
- nitric-oxide synthase activity [IDA, ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- scaffold protein binding [ISO]
- sodium channel regulator activity [ISO]
Gene Ontology Cellular Component
- azurophil granule [ISO]
- cytoplasm [ISO]
- cytoskeleton [IDA]
- cytosol [IBA, ISO]
- dendrite [ISO]
- membrane [ISO]
- membrane raft [IDA]
- mitochondrial outer membrane [ISO]
- mitochondrion [ISO]
- nuclear membrane [ISO]
- nucleus [ISO]
- perinuclear region of cytoplasm [ISO]
- photoreceptor inner segment [ISO]
- plasma membrane [ISO]
- postsynaptic density [ISO]
- protein complex [ISO]
- sarcolemma [IDA, ISO]
- sarcoplasmic reticulum [ISO]
- synapse [IDA, ISO]
- vesicle membrane [ISO]
Mus musculus
Far Western
An interaction is detected between a protein immobilized on a membrane and a purified protein probe.
Publication
gamma-Syntrophin scaffolding is spatially and functionally distinct from that of the alpha/beta syntrophins.
The syntrophins are a family of scaffolding proteins with multiple protein interaction domains that link signaling proteins to dystrophin family members. Each of the three most characterized syntrophins (alpha, beta1, beta2) contains a PDZ domain that binds a unique set of signaling proteins including kinases, ion and water channels, and neuronal nitric oxide synthase (nNOS). The PDZ domains of the ... [more]
Exp. Cell Res. Oct. 01, 2006; 312(16);3084-95 [Pubmed: 16857187]
Throughput
- Low Throughput
Curated By
- BioGRID